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Background/Aims: With the advance of antibiotics and the development of newer imaging techniques, marked changes in etiology, diagnosis; treatment and prognosis of liver abscess have been reported. Methods: We reviewed the clinical data related to 94 patients with pyogenic liver abscess. Results j Of the 94 patients in the study group, the male to female ratio was 1.4:1 and the peak incidence of liver abdess was in the 7th decade. About three quaters (74.5%) of the abcesses were of unknown origin. The predominant location was in the right Iobe (70.3%). Single lesion was found in 80 patients .and . multiple lesions in 14 patients. Pathogens Were identified in 67 patients, of which Kiebsiella pneumonine. (65.7%) and E coil (16.4%) were the most common. The modalities of treatment were percutaneous drainage with antibiotics (73.4%), percutaneous aspiration with antibiotics (16.0%), or antibiotics alone (8.5%). The case fatality rate, mainly from associated underlying diseases, was 9 cases (9.6%). Associated diseases were diabetes mellitus (14.9%) and malignancy (10.6%). Conclusions: Our study revealed that the most common organism was Klebsiella pneumoniae and percutaneous needle aspiration and/or catheter drainage were safe and effective treatment modalities for pyogenic liver abscess. Prognosis was determined by the underlying condition.(Korean J Hepatol 2003;12:275-283)
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